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MITRAL ANNULAR DISJUNCTION AND ARRHYTHMIC RISK: A CASE REPORT
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  • Greta Pascariello,
  • Nicola Berlinghieri,
  • Giuliana Cimino,
  • Emiliano Calvi,
  • Davide Farina ,
  • Edoardo Pancaldi,
  • Angelica Cersosimo,
  • Ludovica Amore,
  • Fabio Alghisi,
  • Enrico Vizzardi,
  • Nicola Bernardi
Greta Pascariello
University of Brescia
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Nicola Berlinghieri
Valduce Hospital
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Giuliana Cimino
University of Brescia
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Emiliano Calvi
University of Brescia
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Davide Farina
University of Brescia
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Edoardo Pancaldi
University of Brescia
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Angelica Cersosimo
University of Brescia
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Ludovica Amore
University of Brescia
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Fabio Alghisi
University of Brescia
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Enrico Vizzardi
University of Brescia
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Nicola Bernardi
University of Brescia
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Abstract

Mitral annular disjunction (MAD) is a structural abnormality of the mitral annulus, defined by a detachment of the atrial wall-mitral valvular junction from the left ventricular (LV) free wall. This structural abnormality in mitral annulus fibrosus is significantly associated with the presence of mitral valve prolapse (MVP) [1], but it can be also detected in normal cases as an anatomical variation of the mitral annulus fibrosus [2]. The main tools to detect MAD are echocardiography and cardiac magnetic resonance. Prevalence of MAD in the general population ranges from 7% [1] to 9% [2]. Several studies proved an association between MAD and arrhythmic events, independently of concomitant mitral valve abnormalities, suggesting the existence of a novel entity: MAD arrhythmic syndrome [3]. Herein we describe a case report of a middle age man with MAD who experienced ventricular arrhythmias and placement of an implantable cardioverter-defibrillator (ICD).

Peer review status:UNDER REVIEW

12 Dec 2020Submitted to Echocardiography
16 Dec 2020Submission Checks Completed
16 Dec 2020Assigned to Editor
29 Dec 2020Reviewer(s) Assigned
15 Jan 2021Review(s) Completed, Editorial Evaluation Pending
25 Jan 2021Editorial Decision: Revise Major
14 Mar 20211st Revision Received
12 Apr 2021Submission Checks Completed
12 Apr 2021Assigned to Editor
13 Apr 2021Reviewer(s) Assigned
25 Apr 2021Review(s) Completed, Editorial Evaluation Pending
09 May 2021Editorial Decision: Revise Minor
07 Jun 20212nd Revision Received
08 Jun 2021Submission Checks Completed
08 Jun 2021Assigned to Editor
08 Jun 2021Reviewer(s) Assigned