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Lymphomatoid granulomatosis of the central nervous system (CNS-LYG), immune thrombocytopenia, disseminated zoster and venous thrombosis: “Hickam’s dictum posing a management challenge”
  • +6
  • Mohsin Soleja,
  • Jesse Jaso,
  • Weina Chen,
  • Jack Raisanen,
  • Christian Wysocki,
  • Yu-Min Shen,
  • Bruce Mickey,
  • Kiran Kumar,
  • Praveen Ramakrishnan Geethakumari
Mohsin Soleja
UT Southwestern
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Jesse Jaso
The University of Texas Southwestern Medical Center
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Weina Chen
UT Southwestern Medical School
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Jack Raisanen
The University of Texas Southwestern Medical Center
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Christian Wysocki
UT Southwestern Medical Center
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Yu-Min Shen
University of Texas Southwestern Medical Center
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Bruce Mickey
The University of Texas Southwestern Medical Center
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Kiran Kumar
The University of Texas Southwestern Medical Center
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Praveen Ramakrishnan Geethakumari
University of Texas Southwestern Medical Center at Dallas
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Abstract

We describe a case of isolated primary CNS lymphomatoid granulomatosis and a discordant low-grade B-cell lymphoma involving the bone marrow causing chronic immune thrombocytopenia. Clinical course was complicated with disseminated zoster and sub-massive pulmonary embolism. Our patient was successfully managed with a combination radioimmunotherapy strategy with rituximab and radiation therapy.

Peer review status:UNDER REVIEW

09 Jan 2021Submitted to Clinical Case Reports
11 Jan 2021Assigned to Editor
11 Jan 2021Submission Checks Completed
20 Jan 2021Reviewer(s) Assigned