Persistently Elevated Urine β2-MG and Decreased BMD in a Patient with
ADV-induced Hypophosphatemic Osteomalacia and Fanconi’s Syndrome After
Drug Withdrawal
Abstract
This is the first case of adefovir dipivoxil (ADV)-induced
hypophosphatemic osteomalacia (HO) and Fanconi’s syndrome in which bone
mineral density (BMD) is continuously reduced after drug
discontinuation. Sustained elevation of urine β2-MG also supports the
recent view that ADV-induced renal injury is not completely reversible.