Posttransfusion hyperhemolysis syndrome in beta thalassemia major:
Postulation of various mechanisms
Abstract
Hyperhemolysis syndrome (HS) should be considered in a multiply
transfused thalassemia patient. HS in this patient was attributed to a
combination of factors including multiple transfusions, presence of
anti-Cw, macrophage hyperactivity, hypersplenism and suppression of
erythropoiesis.
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