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Epidemiologic and clinical characteristics of 3334 cases with pre-diagnosis coronavirus disease - 2019 (COVID-19) in Turkey
  • Nur Simsek Yurt,
  • Metin Ocak,
  • Yusuf Can Yurt
Nur Simsek Yurt
Samsun Education and Research Hospital
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Metin Ocak
Gazi State Hospital
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Yusuf Can Yurt
Gazi State Hospital
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Abstract

Introduction: As COVID-19 disease has rapidly spread across the world, its impact has grown with increasing number of cases and mortality rate in Turkey. Aim: The aim of this study is to examine epidemiologic and clinical features of the patients that admitted to the hospital with the pre-diagnosis of coronavirus disease-2019 (COVID-19) in Turkey. Method: In this retrospective study, epidemiologic and clinical features, laboratory findings, radiologic features, therapeutic approaches and survival conditions of the patients with the pre-diagnosis of COVID-19 from March 11th to June 30th, 2020. The all data of the cases were compared in 4 groups: 1st group for the confirmed cases reverse transcriptase polymerase chain reaction (RT-PCR) +, chest computed tomography (CT) +, 2nd group for the clinically diagnosed cases (RT-PCR- CT +), 3rd group for the mild and asymptomatic cases (RT-PCR + CT-), 4th group for the suspected cases (RT-PCR - CT -). Post-hoc analysis was performed to evaluate the differences among the groups. Results: In total, 3334 patients with the pre-diagnosis of COVID-19 admitted to the emergency department. Based on the post-hoc analyses, significant differences were found among the four groups in terms of their test results of leucocytes, hemoglobin, platelets, neutrophils, urea and C-reactive protein (CRP) (p<0.001). Furthermore, the factors of age groups, hospitalization, intensive care follow-up and mortality rate of the four groups showed a significant difference among the groups (p=0.001). Conclusion: Mean of leucocytes, neutrophile and platelet values of the patients with tested positive for the RT-PCR was found lower compared to the ones with tested negative for the RT-PCR. Mean of CRP values was found higher in patients with lung involvement compared to other patient groups.

Peer review status:ACCEPTED

21 Jan 2021Submitted to International Journal of Clinical Practice
23 Jan 2021Submission Checks Completed
23 Jan 2021Assigned to Editor
01 Feb 2021Reviewer(s) Assigned
01 May 2021Review(s) Completed, Editorial Evaluation Pending
13 May 20211st Revision Received
14 May 2021Submission Checks Completed
14 May 2021Assigned to Editor
14 May 2021Review(s) Completed, Editorial Evaluation Pending
10 Jun 2021Editorial Decision: Accept