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Clinical-radiological correlations in COVID-19-related venous thromboembolism: preliminary results from a multidisciplinary study
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  • Maddalena Wu,
  • Riccardo Colombo,
  • Massimo Arquati,
  • Sonia Ippolito,
  • Alba Taino,
  • Diego Ruggiero,
  • Francesca Tonelli,
  • Lucia Trombetta,
  • Pietro Facchinetti,
  • Pierluigi Glielmo,
  • Chiara Cogliati,
  • Nicola Flor
Maddalena Wu
ASST Fatebenefratelli Sacco
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Riccardo Colombo
ASST Fatebenefratelli Sacco
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Massimo Arquati
ASST Fatebenefratelli Sacco
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Sonia Ippolito
ASST Fatebenefratelli Sacco
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Alba Taino
ASST Fatebenefratelli Sacco
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Diego Ruggiero
ASST Fatebenefratelli Sacco
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Francesca Tonelli
ASST Fatebenefratelli Sacco
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Lucia Trombetta
ASST Fatebenefratelli Sacco
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Pietro Facchinetti
ASST Fatebenefratelli Sacco
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Pierluigi Glielmo
ASST Fatebenefratelli Sacco
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Chiara Cogliati
ASST Fatebenefratelli Sacco
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Nicola Flor
ASST Fatebenefratelli Sacco
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Abstract

Introduction: Among the multiple complex pathophysiological mechanisms underlying COVID-19 pneumonia, immunothrombosis has been shown to play a key role. One of the most dangerous consequences of the prothrombotic imbalance is the increased incidence of micro- and macro-thrombotic phenomena, especially deep vein thrombosis (DVT) and pulmonary embolism (PE). Methods: We investigated the correlation between radiological and clinical-biochemical characteristics of a cohort of hospitalized COVID-19 patients. Results: PE was confirmed in 14/61 (23%) patients, five (35.7%) had DVT. The radiographic findings, quantified by Qanadli score, correlated with the clinical score and biochemical markers. The ratio between the right and left ventricle diameter measured at CT scan correlated with the length of hospital stay. Conclusion: In our cohort radiological parameters showed a significant correlation with clinical prognostic indices and scores, thus suggesting that a multidisciplinary approach is advisable in the evaluation of PE in COVID-19 patients.

Peer review status:ACCEPTED

12 Feb 2021Submitted to International Journal of Clinical Practice
13 Feb 2021Submission Checks Completed
13 Feb 2021Assigned to Editor
16 Feb 2021Reviewer(s) Assigned
27 Mar 2021Review(s) Completed, Editorial Evaluation Pending
18 Apr 20211st Revision Received
19 Apr 2021Submission Checks Completed
19 Apr 2021Assigned to Editor
19 Apr 2021Reviewer(s) Assigned
10 May 2021Review(s) Completed, Editorial Evaluation Pending
11 May 2021Editorial Decision: Accept