Risk factors for lower respiratory tract infection associated with
tracheobronchial foreign body aspiration in children
Abstract
Background: Tracheobronchial foreign body aspiration (TFBA) is a major
cause of death in children. There are few reports about lower
respiratory tract infection (LRTI) caused by TFBA. This study collected
the TFBA in our hospital to analyze the LRTI and to determine its risk
factors. Methods: A total of 194 children who were performed TFBA
extraction in The Children’s Hospital of Zhejiang University School of
Medicine between June 2019 and April 2020 were enrolled. The clinical
data, cervicothoracic CT and operation records were collected.
Chi-square test, rank sum test and multivariate logistics regression
analysis were applied. Results: The incidence of LRTI was 46.6%, 68.6%
and 68.6% respectively when retention time was within 24 hours, 1 week
and more than 1 week. Cervicothoracic CT showed embedding site in and
above trachea in 24 cases, in main bronchus in 134 cases, in segmental
bronchus and below in 36 cases. Cervicothoracic CT showed no obvious
abnormality in 60 cases, obstructive emphysema or atelectasis in 77
cases, obstructive pneumonia in 50 cases, and the rest in 7 cases.
Cervicothoracic CT diagnosis and retention time of TFBA were different
between LRTI group and non-LRTI group in univariate analysis. There was
a correlation between the retention time of TFBA and LRTI in
multivariate logistics regression analysis. Conclusionss: The incidence
of LRTI caused by TFBA is high. There was no difference in the incidence
of LRTI between organic and inorganic TFBA. The retention time of TFBA
is an independent risk factor for LRTI.