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Comparison of Rapid Antibody Test and Thorax Computed Tomography Results in Patients who Underwent RT-PCR with the Pre-Diagnosis of COVID-19
  • İlker Kızıloglu,
  • Aslı Şener,
  • Neslihan Siliv
İlker Kızıloglu
Dr. Suat Seren Göğüs Hastalıkları ve Cerrahisi Eğitim ve Araştırma Hastanesi
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Aslı Şener
Bakırçay Üniversitesi Çiğli Eğitim ve Araştırma Hastanesi
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Neslihan Siliv
Bakircay Universitesi Cigli Egitim ve Arastirma Hastanesi
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Abstract

Introduction: In this study, it is planned to compare the RT-PCR test, which is the gold standard in the diagnosis of COVID-19, with Thorax computed tomography (CT) and rapid antibody test results. Methods: Patients who were admitted to the emergency service of İzmir Çiğli Training and Research Hospital between 01.04.2020 and 31.05.2020 and who were suspected of having COVID-19 infection were included in the study. The medical records of the patients were retrospectively analyzed through the hospital data processing database. Age, gender, hospitalization, status of home quarantine, real-time reverse transcription-polymerase chain reaction (RT-PCR), thorax CT and rapid antibody test results of the patients were examined. The relationship between RT-PCR, thorax CT and rapid antibody test results were compared statistically. Results: A total of 181 patients, 115 (63.5%) male and 66 (36.5%) female, with an average age of 56.4 ± 18.06 years were included in the study. The nasopharyngeal swab PCR result obtained at the first admission of the patients to the emergency department was positive in 71 (39.2%) patients. Thorax CT was performed in 173 (95.6%) patients who applied to the emergency department, and 112 (64.7%) of them had findings that could be compatible with COVID-19. According to the thorax CT findings in patients, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for detecting COVID-19 infection were respectively; 76.1%, 43.1%, 48.2% and 72.1% (ĸ: 0.176, p <0.001). In our study, the mortality rate for COVID-19 was found to be 2.8%. Conclusion: Rapid antibody test and thorax CT examinations were found to have low diagnostic value in patients who admitted to the emergency department of our hospital and whose first RT-PCR SARS-CoV-2 test was positive. Studies involving larger patient groups are needed for their use alone in diagnosis and screening.

Peer review status:ACCEPTED

10 Feb 2021Submitted to International Journal of Clinical Practice
10 Feb 2021Submission Checks Completed
10 Feb 2021Assigned to Editor
20 Feb 2021Reviewer(s) Assigned
23 Feb 2021Review(s) Completed, Editorial Evaluation Pending
15 May 20211st Revision Received
21 May 2021Submission Checks Completed
21 May 2021Assigned to Editor
21 May 2021Review(s) Completed, Editorial Evaluation Pending
10 Jun 2021Editorial Decision: Accept