Risk factors for acute kidney injury in elderly patients after coronary
artery bypass grafting: A Chinese population
Background and aim of the study: Elderly patients are more likely to
have adverse complications after coronary artery bypass grafting (CABG).
There are few studies on the risk factors for acute kidney injury (AKI)
after surgery in elderly patients, especially in the Asian population.
This study retrospectively analysed the risk factors for AKI in Chinese
elderly patients after CABG and established a risk prediction model to
detect these risk factors early and take active intervention measures.
Methods: A total of 432 patients were included in this study from 2018
to 2019. AKI was defined according to the Kidney Disease Improving
Global Outcomes (KDIGO) criteria. The patients were divided into an AKI
group and a non-AKI group. Multivariate logistic regression analysis was
used to screen out the factors with p < 0.05. Results: Out of
432 patients in the study, 119 (27.5%) developed AKI. The estimated
glomerular filtration rate (eGFR), ≥3 coronary anastomoses, preoperative
intra-aortic balloon pump (IABP) implantation and prolonged ventilation
time were independent risk factors for AKI. The area under the ROC curve
was 0.702 (95% confidence interval (CI) [0.643-0.761], p
< 0.001). Conclusions: The eGFR, ≥3 coronary anastomoses,
preoperative IABP implantation and prolonged ventilation time are
independent risk factors for AKI in elderly patients undergoing coronary
artery bypass grafting. Early discovery of these risk factors and the
implementation of appropriate intervention measures are useful to reduce
the occurrence of AKI after CABG and improve the prognosis of patients.