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Comparison of Transcutaneous Tibial Nerve Stimulation (TTNS) Protocols for Women With Refractory Overactive Bladder (OAB), a Prospective Randomised Trial
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  • Okan ALKIŞ,
  • Mehmet Sevim,
  • Ibrahim Kartal,
  • Aykut Baser,
  • Halil Ivelik,
  • Bekir Aras
Okan ALKIŞ
Kutahya Saglik Bilimleri Universitesi
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Mehmet Sevim
Kutahya Saglik Bilimleri Universitesi
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Ibrahim Kartal
Kutahya Saglik Bilimleri Universitesi
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Aykut Baser
Hitit University
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Halil Ivelik
Kutahya Saglik Bilimleri Universitesi
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Bekir Aras
Kutahya Saglik Bilimleri Universitesi
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Abstract

Objectives: Transcutaneous Tibial Nerve Stimulation (TTNS) is a non-invasive method used in OAB treatment. We aimed to compare the effectiveness of the once a week and three times a week TTNS procedure in women diagnosed with wet type refractory OAB. Methods: A total of 60 patients diagnosed with wet type OAB was refractory to medical treatment included in the study. Participants were equally and randomly divided into two groups: TTNS treatment was performed with a time duration of 30 minutes for 12 weeks, once a week to Groıp-I and three times a week to Group-II. Pre and post-treatment OAB-V8/ICIQ-SF scores and voiding frequencies recorded in the bladder diary were compared between groups. Results: Four patients in Group-1 and eight in Group-2 left the study without completing the treatment. TTNS was performed in both groups for 12 weeks. There was a significant decrease in the voiding frequency, OAB-V8, ICIQ-SF scores in both group-1 and group-2 (p<0.001). A significant decrease in the OAB-V8 score was observed in the 5th week in Group-1, and on the 3rd week in group-2. Complete response was observed in 6 patients (23.1%) in Group-1 after 12 weeks of TTNS procedure. In group-2, 10 patients (45.5%) had a complete response. After the 12-week TTNS procedure, no significant difference was observed between the groups in terms of treatment response. Conclusion: TTNS can be safely used before invasive treatments in resistant OAB. TTNS procedure three times a week seems more effective than performing it once a week.

Peer review status:ACCEPTED

20 Feb 2021Submitted to International Journal of Clinical Practice
22 Feb 2021Submission Checks Completed
22 Feb 2021Assigned to Editor
22 Feb 2021Reviewer(s) Assigned
26 Apr 2021Review(s) Completed, Editorial Evaluation Pending
04 May 20211st Revision Received
04 May 2021Submission Checks Completed
04 May 2021Assigned to Editor
04 May 2021Review(s) Completed, Editorial Evaluation Pending
04 May 2021Editorial Decision: Accept