Three-dimensional speckle tracking echocardiography in evaluating left
ventricular function in patients with triple vessel coronary artery
disease
Abstract
AIM Using three-dimensional ultrasound speckle tracking echocardiography
(3D-STE) to evaluate left ventricular (LV) function in patients with
triple vessel coronary artery disease(TVD) without myocardial
infarction. METHODS Sixty patients with TVD without myocardial
infarction were divided into two groups according to the results of
coronary angiography. Group B (n=31):50%≤the stenosis rate of all
triple vessel coronary artery<75%; Group C (n=29):the stenosis rate
of all triple vessel coronary artery≥75%. Thirty healthy subjects were
recruited as the group A. We measured LV end-diastolic and end-systolic
volume (LVEDV, LVESV) and LV ejection fraction (LVEF) using real-time
dynamic three-dimensional echocardiography. The 3D-STE parameters of LV
included global longitudinal strain (GLS), global area strain (GAS),
global radial strain (GRS) and global circumferential strain (GCS). The
correlation between 3D-STE parameters and NT-proBNP were analyzed by
Pearson linear correlation analysis. RESULTS In group C, LVEDV and LVESV
were significantly increased (all P<0.05), while LVEF, GLS, GRS, GCS
and GAS were significantly decreased compared with groups A and B (all
P<0.05). In groups A and B, there were no statistical differences in
LVEDV, LVESV and LVEF. However, GLS, GCS and GAS were lower in group B
than in group A (all P<0.05). The correlation analysis showed a
negative correlation between the absolute values of GLS, GRS, GCS, GAS
and NT-proBNP in group C
(r=-0.866、-0.587、-0.428、-0.600,P<0.001、P=0.001、P=0.020、P=0.010).
CONCLUSIONS Our study shows that 3D-STE can evaluate the LV function in
patients with triple vessel coronary artery disease without myocardial
infarction through multiple strain parameters.