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Recent Advances in Gene Therapy for Atrial Fibrillation
  • +2
  • Shin Yoo,
  • Gail Geist,
  • Anna Pfenniger,
  • Markus Rottmann,
  • Rishi Arora
Shin Yoo
Northwestern University Feinberg School of Medicine
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Gail Geist
Northwestern University Feinberg School of Medicine
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Anna Pfenniger
Northwestern University
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Markus Rottmann
Northwestern University Feinberg School of Medicine
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Rishi Arora
Northwestern University
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Abstract

Atrial fibrillation (AF) is the most common heart rhythm disorder in adults and a major cause of stroke. Unfortunately, current treatments for AF are suboptimal as they are not targeting the molecular mechanisms underlying AF. In this regard, gene therapy is emerging as a promising approach for mechanism-based treatment of AF. In this review, we summarize recent advances and challenges in gene therapy for this important cardiovascular disease.

Peer review status:UNDER REVIEW

26 Feb 2021Submitted to Journal of Cardiovascular Electrophysiology
03 Mar 2021Assigned to Editor
03 Mar 2021Submission Checks Completed
03 Mar 2021Reviewer(s) Assigned