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Very high-power short-duration temperature-controlled ablation versus conventional ablation-index guided power-controlled ablation for pulmonary vein isolation
  • +13
  • Roland Tilz,
  • Makoto Sano,
  • Julia Vogler,
  • Thomas Fink,
  • Roza Meyer-Saraei,
  • Vanessa Sciacca,
  • Bettina Kirstein,
  • Huong Lan Phan,
  • Sascha Hatahet,
  • Behzad Fahimi,
  • Lisbeth Delgado Lopez,
  • Anna Traub,
  • Charlotte Eitel,
  • Michael Schlueter,
  • Karl-Heinz Kuck,
  • Christian Heeger
Roland Tilz
University Hospital of Lubeck
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Makoto Sano
Hamamatsu University School of Medicine
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Julia Vogler
University Heart Center Lübeck
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Thomas Fink
University Heart Center Lübeck
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Roza Meyer-Saraei
University Heart Center Lübeck
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Vanessa Sciacca
University Heart Center Luebeck
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Bettina Kirstein
University Heart Center Luebeck
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Huong Lan Phan
University Hospital Schleswig-Holstein
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Sascha Hatahet
University Heart Center Luebeck
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Behzad Fahimi
University Hospital Schleswig-Holstein
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Lisbeth Delgado Lopez
University Heart Center Luebeck
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Anna Traub
University Heart Center Luebeck
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Charlotte Eitel
University Heart Center Lübeck
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Michael Schlueter
University Heart Center Luebeck
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Karl-Heinz Kuck
Asklepios Klinik St. Georg
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Christian Heeger
AK St. Georg
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Abstract

Background: Catheter ablation for atrial fibrillation (AF) treatment provides effective and durable pulmonary vein isolation (PVI) and is associated with encouraging clinical outcome. A novel CF sensing temperature-controlled radiofrequency (RF) ablation catheter allows for very high-power short-duration (vHP-SD, 90W/4 seconds) ablation aiming a potentially safer, more effective and faster ablation. We thought to evaluate preliminary safety and efficacy of vHP-SD ablation for PVI utilizing a novel vHP-SD catheter. The data was compared to conventional power-controlled ablation index (AI) guided PVI utilizing conventional contact force (CF) sensing catheters. Methods and Results: Fifty-six patients with paroxysmal or persistent AF were prospectively enrolled in this study. Twenty-eight consecutive patients underwent vHP-SD based PVI (vHP-SD group) and were compared to 28 consecutive patients treated with conventional CF-sensing catheters utilizing the AI (control group). All PVs were successfully isolated using vHP-SD. The median RF ablation time for vHP-SD was 338 (IQR 286, 367) seconds vs control 1580 (IQR 1350, 1848) seconds (p<0.0001), the median procedure duration was vHP-SD 55 (IQR 48-60) minutes vs. control 105 (IQR 92-120) minutes (p<0.0001). No differences in periprocedural complications were observed. Conclusions: This preliminary data of the novel vHP-SD ablation mode provides safe and effective PVI. Procedure duration and RF ablation time were substantially shorter in the vHP-SD group in comparison to the control group.