Efficacy of hemoadsorption using HA330-II perfusion column in secondary
HLH patients: two cases report and literature review.
Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a severe and
potentially lethal disorder characterized by overwhelming immune
activation and inflammation. Several blood purification methods have
been reported to be successfully practiced as adjuvant therapy for
hypercytokinamia complicated with HLH. We firstly reported two cases of
secondary HLH children received hemoadsorption therapy with HA330-II
perfusion cartridge combined with CVVHDF. The marked decrease in IL-6
plasma levels and stabilization of organ function were observed after
treatment, which proved the efficiency of HA330-II perfusion column.
Keywords: hemoadsorption, blood purification, Hemophagocytic