EVALUATION OF THE RELATIONSHIP BETWEEN DENTAL CARIES AND OXIDATIVE
STRESS AND ANTIOXIDANT CAPACITY
Abstract
Background Dental caries can be affected or altered by the body’s
oxidant / antioxidant balance and oxidative stress. Aim/Hypothesis To
examine the relationship between dental caries and Total Oxidant Status
(TOS), Total Antioxidant Status (TAS), and Oxidative Stress Index (OSI).
Design The study group consisted of 52 children with dental caries
(DMFS/dfs ≥ 5), and the control group consisted of 42 healthy children
(DMFS/dfs = 0). The saliva samples, unstimulated and mid-morning, were
collected from all children. Participants’ saliva samples were acquired
by spitting for 5 minutes, after which the samples were frozen and
stored at 4 ° C and kept at -80 ° C until analysis. NCSS (Number
Cruncher Statistical System) 2007 (Kaysville, Utah, USA) was used for
the statistical analysis. Results TOS of the patient group cases were
statistically significantly higher than those of the control group
(p=0,004; p<0,01). OSI values of the patient group cases were
statistically significantly higher than those of the control group
(p=0,008; p<0,01). Conclusion OSI and TOS as markers of
oxidative stress levels were found to be significantly higher in the
group of patients with dental caries than in the healthy group.