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Molecular allergology and its impact in specific allergy diagnosis and therapy
  • +5
  • Domingo Barber Hernández,
  • Araceli Diaz Perales,
  • Maria Escribese,
  • Jörg Kleine-Tebbe,
  • Paolo Matricardi,
  • Markus Ollert,
  • Alexandra Santos,
  • Joaquin Sastre
Domingo Barber Hernández
Universidad San Pablo CEU
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Araceli Diaz Perales
Centro de Biotecnologia y Genomica de Plantas
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Maria Escribese
Universidad CEU San Pablo
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Jörg Kleine-Tebbe
Berlin, Germany
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Paolo Matricardi
Charitè University Medical Center
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Markus Ollert
Luxembourg Institute of Health
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Alexandra Santos
King's College London
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Joaquin Sastre
Fundacion Jimenez Diaz
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Abstract

Progressive knowledge of allergenic structures resulted in a broad availability of allergenic molecules for diagnosis. Component resolved diagnosis allowed a better understanding of patient sensitization patterns, facilitating allergen immunotherapy decisions. In parallel to the discovery of allergenic molecules, there was a progressive development of a regulation framework that affected both in vitro diagnostics and Allergen Immunotherapy products. With a progressive understanding of underlying mechanisms associated to Allergen immunotherapy and an increasing experience of application of molecular diagnosis in daily life, we focus in analyzing the evidences of the value provided by molecular allergology in daily clinical practice, with a focus on Allergen Immunotherapy decissions.

Peer review status:ACCEPTED

31 Mar 2021Submitted to Allergy
01 Apr 2021Submission Checks Completed
01 Apr 2021Assigned to Editor
07 Apr 2021Reviewer(s) Assigned
30 Apr 2021Review(s) Completed, Editorial Evaluation Pending
04 May 2021Editorial Decision: Revise Minor
10 May 20211st Revision Received
11 May 2021Assigned to Editor
11 May 2021Submission Checks Completed
12 May 2021Reviewer(s) Assigned
16 May 2021Review(s) Completed, Editorial Evaluation Pending
18 May 2021Editorial Decision: Revise Minor
19 May 20212nd Revision Received
20 May 2021Submission Checks Completed
20 May 2021Assigned to Editor
25 May 2021Reviewer(s) Assigned
25 May 2021Review(s) Completed, Editorial Evaluation Pending
25 May 2021Editorial Decision: Accept