loading page

Which Non-Muscle Invasive Bladder Cancer Is More Valuable For Re-transurethral resection?
  • +3
  • Murat Akgul,
  • Cagri Dogan,
  • Cenk Murat Yazıcı,
  • Mehmet ŞAHİN,
  • Aysegul Arslan,
  • Meltem Oznur
Murat Akgul
Namik Kemal University Faculty of Medicine

Corresponding Author:[email protected]

Author Profile
Cagri Dogan
Tekirdag Namik Kemal University
Author Profile
Cenk Murat Yazıcı
Namik Kemal University Faculty of Medicine
Author Profile
Mehmet ŞAHİN
Tekirdag Namik Kemal University
Author Profile
Aysegul Arslan
Tekirdag Namik Kemal University
Author Profile
Meltem Oznur
Namik Kemal University Faculty of Medicine
Author Profile

Abstract

INTRODUCTION: We evaluated the re-transurethral resection (re-TUR) pathologies and the comparison of pathology results between transurethral resection of bladder (TUR-B) and re-TUR for non-muscle invasive bladder cancer (NMIBC). Additionally we assessed the factors affecting the re-TUR pathology and tried to define the more valuable re-TUR patient groups. We also aimed to evaluate the effect of re-TUR on recurrence and progression. METHODS: We performed re-TUR to intermediate/high risk NMIBC patients, 4-6 weeks after the index TUR-B. Both TUR-B and re-TUR pathology characteristics, including tumor stage, grade, size, number, lymphovascular invasion (LVI), carcinoma in situ (CIS), variant pathology and intermediate/high risk status were analysed. The recurrence and progression rates were also evaluated according to re-TUR. RESULTS: A total of 78 patients with NMIBC were included to the study. The index TUR-B pathologies were Ta-Low: 6 (7,7%), Ta-High: 5 (6,4%), T1-Low: 14 (17,9%), T1-High: 53 (67,9%). Re-TUR positivity was n: 40 (51 %), and upstaging/upgrading at re-TUR was n: 11 (14 %) in all groups. Re-TUR positivity was significantly higher in high-risk compared to intermediate-risk NMIBC (p:0,026). Re-TUR positivity was higher in patients with hydronephrosis, CIS, LVI, differentiation, size (>3 cm) and multiple tumour presence (p<0,05). There was no significant relationship between recurrence / progression and re-TUR (p>0,05). CONCLUSION: Residual tumour was common after the index TUR-B and upstaging after re-TUR was very important. Re-TUR is critically important in high-risk NMIBC, presence of hydronephrosis, CIS, LVI, variant pathology, size (>3 cm) and multiple number of tumor.