Relationship between gastric intestinal metaplasia and colorectal
neoplasms.
Abstract
Background and aims : Colorectal cancers are one of the most common
types of cancer. Gastric intestinal metaplasia is considered a
precancerous lesion that can progress into gastric cancer. Even though
there are previous publications stating that Helicobacter pylori and
intestinal metaplasia are related to colorectal adenomas, there are also
studies stating the opposite. This study aims to determine the
relationship between gastric intestinal metaplasia and colorectal
neoplasia. Methods: A total of 214 patients between the ages of 19 and
92 who underwent combined gastroscopy and colonoscopy between August
2016 and April 2020 were included in this retrospective study. Medical
records including demographic data, gastroscopy and colonoscopy findings
and histopathology results of the patients were reviewed and analyzed.
The association of intestinal metaplasia and Helicobacter pylori
infection with colorectal neoplasia was evaluated in these patients.
Results: The mean age of the patients included in the study was
49.07±15.80, and 125 (58.4%) of the patients were male. A statistically
significant correlation was found between intestinal metaplasia and
colon neoplasm prevalence (p= 0.03). However, such a correlation was not
seen between Helicobacter pylori and colon neoplasia. Conclusion: A
positive correlation was found between gastric intestinal metaplasia,
which is a precancerous lesion, and colon neoplasia. Even though this
correlation indicates higher prevalence rates of colon neoplasia in
patients with gastric intestinal metaplasia, how to evaluate these
patients in terms of colon neoplasia remains a controversial issue.