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Effects of Duration of Using Intraaortic Balloon Pump on Renal Function and Clinical Outcome
  • Hong-Wu Chen,
  • Yu Xiao-Fan,
  • Li-Kun Ma
Hong-Wu Chen
University of Science and Technology of China
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Yu Xiao-Fan
University of Science and Technology of China
Author Profile
Li-Kun Ma
University of Science and Technology of China
Author Profile

Abstract

Objective:To integrate the effects of duration of using intraaortic balloon pump (IABP) on renal function, major adverse cardiac events (MACEs) and all-cause mortality in patients with acute myocardial infarction (AMI) complicating pump failure. Methods:Between March 2017 and June 2018, a retrospective study enrolled 306 patients with AMI complicating pump failure who underwent coronary artery angiography (CAG) or percutaneous coronary intervention (PCI) was conducted. Patients were divided into the duration ≤4 days and the duration>4 days in basis of median the IABP duration. We compared the renal function parameters at the three time section of IABP implantation between two groups. Analysis of factors of contrast-induced nephropathy (CIN), 12-month MACEs and all-cause mortality were also performed. Results:There were 146 patients in IABP duration ≤4 days and 92 patients in IABP duration > 4 days. Renal function was only correlated with IABP duration instead of timing of IABP implantation. On multivariate analysis, CIN risk increased by 81.2% (RR= 1.812, 95%CI, 1.167–3.763) for every 100mL increment of contrast agent. Hematocrit, blood platelet, IABP use >4 days were significantly inversely associated with CIN. Cox-regression analysis suggested that IABP duration was not significantly correlated with the incidence of 12-month MACEs and all-cause mortality. Conclusion:Longer duration of IABP implantation was beneficial to renal function, but was not significantly correlated with the incidence of 12-month MACEs and all-cause mortality in patients with AMI complicating pump failure. Patients undergoing PCI or CABG should notice that the potential damage of high dose of contrast agents on the renal function.

Peer review status:UNDER REVIEW

28 Mar 2021Submitted to Journal of Cardiac Surgery
29 Mar 2021Assigned to Editor
29 Mar 2021Submission Checks Completed
22 Apr 2021Reviewer(s) Assigned