loading page

Chemoradiation for Pediatric Primary Cardiac Leiomyosarcoma: Case Report and Review of Literature
  • +1
  • James Janopaul-Naylor,
  • Kirk Kanter,
  • Thomas Olson,
  • Bree Eaton
James Janopaul-Naylor
Emory University Winship Cancer Institute
Author Profile
Kirk Kanter
Emory University School of Medicine
Author Profile
Thomas Olson
Emory University School of Medicine
Author Profile
Bree Eaton
Emory University Winship Cancer Institute
Author Profile

Abstract

A 13-year-old healthy girl presented with dizziness and palpitations, found to have a left atrial mass. An 8 cm tumor was removed. Pathology confirmed leiomyosarcoma, Grade 3 with positive margins. She was treated with ifosfamide and doxorubicin prior to radiation with concurrent ifosfamide alone. She was treated to 66 Gy in 33 fractions to the operative bed. Prospectively graded toxicities included Gr 2 esophagitis and Gr 1 anorexia, dermatitis and fatigue. She completed a total of 6 cycles of ifosfamide. One year after treatment she had no evidence of disease with normal ECHO and no cardiac, pulmonary or esophageal symptoms.

Peer review status:IN REVISION

19 Apr 2021Assigned to Editor
19 Apr 2021Submission Checks Completed
19 Apr 2021Submitted to Pediatric Blood & Cancer
23 Apr 2021Reviewer(s) Assigned
25 May 2021Review(s) Completed, Editorial Evaluation Pending
25 May 2021Editorial Decision: Revise Minor