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THE EVALUATION OF LUNG INVOLVEMENT AND FUNCTIONAL CAPACITIES IN PATİENTS DİAGNOSED WITH PRIMARY SJOGREN’S SYNDROME
  • +2
  • Tugce Sahin Ozdemirel,
  • Ali Erhan Ozdemirel,
  • Berna Akinci Ozyurek,
  • Derya Yenibertiz,
  • Yurdanur Erdogan
Tugce Sahin Ozdemirel
Department of Chest Disease, University of Health Sciences Ankara Atatürk Chest Diseases and Chest Surgery Training and Research Hospital, Ankara-Turkey.
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Ali Erhan Ozdemirel
Department of Rheumatology, University of Health Sciences, Gaziler Physical Therapy And Rehabilitation Training And Research Hospital, Ankara, Turkey
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Berna Akinci Ozyurek
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Derya Yenibertiz
University of Health Sciences Keçiören Training and Research Hospital, Ankara-Turkey.
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Yurdanur Erdogan
Department of Chest Disease, University of Health Sciences, Atatürk Chest Diseases and Chest Surgery Training and Research Hospital, Ankara, Turkey
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Abstract

ABSTRACT Introduction: Sjögren syndrome is a chronic, systemic, inflammatory disease characterized with lymphocytic infiltration of the exocrine glands, frequently manifested by dryness in the region affected. Although the most common extraglandular involvement in SS is pulmonary involvement. Early diagnosis and treatment is considered to be important. It was aimed to evaluate the frequency of early lung involvement, high resolution computed tomography (HRCT) findings and data of pulmonary function test (PFT) in SS in this study. Material-Method: Thirty five patients diagnosed with SS and referred by the Department of Rheumatology to determine potential lung involvement to the 8th chest diseases outpatient clinic of our hospital between September 2015 and December 2018 were included in this study. Respiratory signs, demographic features, length of disease and treatment regimens, PFT, data of 6-minute walk test (MWT) and findings of HRCT of the patients were retrospectively obtained from hospital information system and patient files. Results: The mean age of the patients was 54.4 ± 9.2. The majority of the patients were women (94.3%). When the HRCT findings were evaluated, 28 (80%) patients had CT findings, while 7 (20%) patients had no CT findings. The most common HRCT findings found in patients were peribronchial thickening (48.6 %), ground glass appearance (28.6%) and prominence in interstitial scars. Conclusion: We think that the evaluation of HRCT and PFTs in patients diagnosed with SS for assessing early pulmonary involvement will be guiding in terms of follow-up and treatment.

Peer review status:UNDER REVIEW

25 Feb 2021Submitted to International Journal of Clinical Practice
26 Feb 2021Assigned to Editor
26 Feb 2021Submission Checks Completed
30 Apr 2021Reviewer(s) Assigned
15 Jun 2021Review(s) Completed, Editorial Evaluation Pending