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Multiple myeloma with cardiac involvement accompanied by partial superior vena cava obstruction: a case report and literature review
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  • Shuzhen Wang,
  • Ruohan Zhao,
  • Kunyue Tan,
  • Chunxia Liu,
  • Lijuan Zhang,
  • Min Xu,
  • Feng Xiong
Shuzhen Wang
Chengdu Third People's Hospital
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Ruohan Zhao
Chengdu Third People's Hospital
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Kunyue Tan
Chengdu Third People's Hospital
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Chunxia Liu
Chengdu Third People's Hospital
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Lijuan Zhang
Chengdu Third People's Hospital
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Min Xu
Chengdu Third People's Hospital
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Feng Xiong
Chengdu Third People's Hospital
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Abstract

Extramedullary involvement of the endocardium is rare in multiple myeloma. Here we describe a case of multiple myeloma (plasma cell) with extramedullary plasmablastic transformation and endocardial involvement, which resulted in partial superior vena cava obstruction. We also conducted a literature review and summary analysis of space-occupying lesions in the heart in 12 patients with multiple myeloma (including the current case) in the last 10 years. Echocardiography is the preferred radiologic examination method for diagnosis and follow-up in multiple myeloma, and surgical resection is effective for alleviating symptoms.

Peer review status:UNDER REVIEW

11 May 2021Submitted to Echocardiography
11 May 2021Submission Checks Completed
11 May 2021Assigned to Editor
12 May 2021Reviewer(s) Assigned
15 May 2021Review(s) Completed, Editorial Evaluation Pending
20 May 2021Editorial Decision: Revise Major
08 Jun 20211st Revision Received
10 Jun 2021Submission Checks Completed
10 Jun 2021Assigned to Editor
13 Jun 2021Reviewer(s) Assigned