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Bronchoscopic Features and Correlative Factor Analysis of Severe Mycoplasma pneumoniae Pneumonia in Children.
  • haiming yang,
  • Gan Li,
  • Xicheng Liu
haiming yang
Beijing Children's Hospital
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Gan Li
Beijing Children's Hospital
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Xicheng Liu
Beijing Children's Hospital Capital Medical University
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Abstract

Objectives: We aimed to determine the bronchoscopic features of children with severe Mycoplasma pneumoniae pneumonia (SMPP), and correlation with obliterative bronchitis (OB), so as to help early clinical evaluation and treatment of pediatric SMPP. Methods: 213 pediatric SMPP cases admitted to Beijing Children’s Hospital were included. Medical records and bronchoscopic manifestations at different SMPP stages were retrospectively analyzed . Results: Of 213 acute-stage pediatric SMPP patients, bronchoscopy revealed 22 cases (10.3%) with subacute-stage or recovery-stage OB, for an OB incidence rate in cases with mucous embolus of 48.8% (22/47), a significantly higher rate than the rate without mucous embolus (0/166, 0%) (P < 0.001). Notably, the OB incidence rate for children undergoing bronchoscopy within 10 days (9/142, 6.3%) of SMPP onset was significantly lower than in children undergoing bronchoscopy 10 days post-disease onset (13/71, 76.5%) (P < 0.007). Conclusions: In pediatric SMPP patients, airway mucus and debris from epithelial necrosis and exfoliation can block airway subbranches, readily leading to OB.

Peer review status:UNDER REVIEW

01 Feb 2021Submitted to Pediatric Pulmonology
02 Feb 2021Assigned to Editor
02 Feb 2021Submission Checks Completed
20 May 2021Reviewer(s) Assigned