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Reverse remodeling in new onset heart failure and its affection on the right side parameters.
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  • Manal Adel,
  • Yasser Sharaf,
  • Hesham Yehia,
  • Kareem Mahmoud
Manal Adel
Cairo University Kasr Alainy Faculty of Medicine
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Yasser Sharaf
Cairo University Kasr Alainy Faculty of Medicine
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Hesham Yehia
Cairo University Kasr Alainy Faculty of Medicine
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Kareem Mahmoud
Cairo University Kasr Alainy Faculty of Medicine
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Abstract

Background Patient with new onset heart failure showed improvement in their EF and strain pattern along with improvement in cardiac biomarkers followed intervention procedures or device implantation and medical treatment. However right side changes are affected by these changes as well which needed further studies. Methods Hundred patients were included in a period starting from 2018 to 2020 and their follow up after 3-6 months :All patients underwent full assessment including Minnesota questionnaire of heart failure ,examination and echocardiography with focusing on global longitudinal ,circumferential strain ,right side areas and fractional area changes. Troponin I was evaluated at admission and follow up. Results There was significant change between patients at admission and follow up in Minnesta Q questionnaire from19.1±11.6 to 13.8 ±10.4 with P value (0.001) ,and change in troponin I 1.84.9 to 0.1 0.3 with P value <0.001.The Ejection fraction by 2D Simpson method showed statistically significant change from 30.6±8.5 to 41.9±14.0 with P value < 0.001, Moreover ESV index showed a significant decrease from 50.5±21.1 to 37.5±23.2 with P value of 0.017. Global longitudinal strain showed significant increase from 5.9±3.5 to 7.5 ±3.8with P value 0.024. The right side dimensions of end-systolic showed a significant increase from 9.8±4.5 to 8.2 ±3.4 with P value 0.008 .FAC showed a significant increase from a mean of 41.7±10.7 to 45.4 ±8.8 with P value of 0.008 . Conclusion: Significant changes affected the cardiac volumes parameters in reverse remodeled followed medical treatment and/ or revascularization affecting both left and right side parameters..

Peer review status:UNDER REVIEW

12 May 2021Submitted to Echocardiography
28 May 2021Assigned to Editor
28 May 2021Submission Checks Completed
03 Jun 2021Reviewer(s) Assigned