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Two-Case Series of Heart Transplant at a Single Center in a SARS-CoV-2 Epicenter
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  • Marlena Sabatino,
  • Cassandra Soto,
  • Krish Dewan,
  • Joshua Chao,
  • Hirohisa Ikegami,
  • Anthony Lemaire,
  • Mark Russo,
  • Leonard Lee
Marlena Sabatino
Rutgers Robert Wood Johnson Medical School
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Cassandra Soto
Rutgers Robert Wood Johnson Medical School
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Krish Dewan
Rutgers Robert Wood Johnson Medical School
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Joshua Chao
Rutgers Robert Wood Johnson Medical School
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Hirohisa Ikegami
Robert Wood Johnson Foundation
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Anthony Lemaire
Rutgers Robert Wood Johnson Medical School New Brunswick
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Mark Russo
Rutgers Robert Wood Johnson Medical School
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Leonard Lee
Rutgers-Robert Wood Johnson Medical School
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Abstract

As SARS-CoV-2 continues to challenge hospital systems, the safety of heart transplantation must be evaluated. Retrospective review of all heart recipients transplanted at a single academic medical center in a U.S. SARS-CoV-2 epicenter found two patients with non-ischemic dilated cardiomyopathy. The 34-year-old male (ejection fraction <10%) was bridged to transplant with extracorporeal membrane oxygenation and microaxial left ventricular assist device. His perioperative course was uncomplicated except for transient SARS-CoV-2 seropositivity two months post-transplant. He was asymptomatic and remained so eight months to follow. The 20-year-old female (ejection fraction 5%) was bridged to transplant with microaxial left ventricular assist device. She progresses well with SARS-CoV-2 seronegativity eight months post-transplant. Our early experience suggests that intentional recipient, donor, and provider testing, cautious organ procurement, strategic intrahospital patient organization and transport, and well-coordinated follow-up permits uninterrupted provision of this definitive therapy for heart failure without subjecting these patients to greater risk.

Peer review status:UNDER REVIEW

08 Apr 2021Submitted to Journal of Cardiac Surgery
07 Jun 2021Assigned to Editor
07 Jun 2021Submission Checks Completed
08 Jun 2021Reviewer(s) Assigned