Olfactory bulb is not only a site of neurogenesis, but also receives dopaminergic input; therefore, changes in its volume that have been shown to parallel with olfactory recovery should be expected with STN-DBS. Furthermore, with its role in being a phenotypical marker to signify olfactory dysfunction in PD patients, we decided to track changes in OB volume with length of stimulation to determine if this structure can be a predictive marker of olfactory recovery following stimulation.
Behavioral Analysis - Olfaction