Forty-oneconsecutive adult patients (mean age ± SD 34.98 ± 14.18) with clinicaldiagnosis of dengue were enrolled in this study. 25 patients were classified as having dengue fever (DF) and16 patients as having dengue hemorrhagic fever (DHF). The DF group did notdiffer from DHF group with regard to ageand sex. The 30 adults in the healthy control group were similar to the denguedisease groups in age and sex (data not shown). Thefigure 1 shows the lipid profile for each group of dengue disease andcontrol. Patients who had DF were compared with patients who had DHF andhealthy control subjects wich revealed that groups differed significantly with regard to serum lipid profile according toANOVA test (p =< 0.05). The lowestlevels of cholesterol (106 ± 26.42 mg/dl) LDL (58.38 ± 18.37 mg/dl) and HDL (20.81± 10.11 mg/dl) were observed in DHF patients compared with DF and controlsubjects (figure 1). On the other hand highest levels of triglycerides (169 ± 76.17mg/dl) and VLDL (33.96 ± 15.23 mg/dl) wereobserved in DHF patients compared with DF and control subjects (figure1). Significantly increased in mean TNF-α values were observed in a group of 16patients with dengue infection (21.94±7.50 pg/mL) when was compared to thehealthy control group (14.16±10.40 pg/mL) (p= 0.0058). Nevertheless Statistically TNF-α level did not correlate with lipids levels in patients withdengue (Table 1).