Temporal dynamics of whole-brain inter-subject correlation and inter-subject functional connectivity. a, the distribution of subjects’ global ISC values on each day of practicing the learning task. ISC increased from day one to day two of task practice, and then decreased in day three and day four. b, the distribution of subjects’ global ISFC values on each day of practicing the learning task. ISC increased from day one to day two of task practice, and then remained relatively stable. (C) The temporal dynamics of the normalized ISC and ISFC; while both peak on day two; ISFC becomes significantly higher in day four.