Next, we assessed the degree to which the time-dependent variation in ISC and ISFC might differ across the seven brain modules (Fig. 5). We observed that all of the modules display similar profiles of ISFC and ISC as shown for the whole brain in Figure 3E. For all modules, ISC was initially higher than ISFC on day one. On day two, ISFC becomes higher than ISC. Finally, both ISC and ISFC decrease on days three and four; however, in all modules besides the FT module, ISFC remains equal to or higher than ISC. This pattern of findings implies that the temporal evolution of inter-subject connectivity and activity is similar across the entire brain, and that high ISC dominates early in learning, while high ISFC dominates later in learning.