Conclusion
In patients undergoing SE, disagreement in site versus core lab interpretations was infrequent and occurred with both rest and stress assessments. Discordance was most commonly due to an abnormal site read when normal by core lab, and led to additional noninvasive and invasive testing. Attention to identifiable patient and imaging characteristics may reduce interpretive variation and reduce downstream testing.
Other refs to look up:
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Redelmeier DA, Shafir E. Medical decision making in situations that offer multiple alternatives. JAMA. 1995;273(4):302–5. doi: 10.1001/jama.1995.03520280048038.