Pharmacokinetic profiles of resveratrol and pterostilbene after 14 days of oral dosing are depicted in Fig. 2; similar results were seen in animals receiving a single oral dose (data not shown). After administration of equimolar doses, plasma concentrations of pterostilbene were substantially greater than were plasma concentrations of resveratrol at both dose levels evaluated in the study. The bioavailability of both resveratrol and pterostilbene appeared to be largely independent of the dose (over the 3-fold dose range used in the study) and number of doses (1 or 14; Table 3); at both doses and durations of exposure, the bioavailability of pterostilbene was approximately 3- to 4-fold greater than was the bioavailability of resveratrol. This finding is consistent with much greater Cmax and AUC0–inf values for pterostilbene.