Introduction :
Hemophagocytic syndromes (HS) have experienced a very significant
revival in recent years, there are considered as a rare pathology but a
lot of progress has been made thanks to improved knowledge and the
multiplication of publications and the establishment of well-coded
protocol for treating this syndrome.
HS have poor diagnosis, it can be definded by overstimulation of the
immune system leading to systemic inflammation, cytokine storm and
multi-organ failure.1
They constitute a heterogeneous group and can be divided into two
primary hemophagocyte categories lymphohistiocytosis (HLH) and secondary
hemophagocytic syndromes.2
Herein we report a rare case of a woman with stage secondary HLH to
Hepatitis B virus (HBV) and hepatitis C virus (HCV) coinfection, the
first case in Morocco to our knowledge. The patient achieved complete
remission with antiviral treatment and chemotherapy. Through this work
we highlight the need of more research and collaboration across all
physicians as well as sharing information about similarities and
differences between cases, and about their management to improve the
overall prognosis and to raise awareness about this malignancy among
physicians and patients.