Approaches discrepancies

As experimental techniques becomes more sophisticated, such as the using of reporter genes and  imaging techniques, more in situ specific data can be taken into account for the study of plasmid dynamics in a more realistic way. The general assumption of mass action of population and stochastic models only works for well mixed environments. Which is not the case on spatially structure nature systems.  In this scenarios, ecological interactions between populations could be better understood using individual-based models. \citep{S_rensen_2005}
This modeling framework can integrate individual specific characteristics and as the the number of processes involved increases so does the programming and computational complexity. Nonetheless, this approach becomes very useful in studying communities ecological interactions in spatially structured manner. The advantage of this models is that they can efficiently capture population dynamics from individuals interactions, that at the same time this interactions are driven by properties that could or not vary between individuals of the same type. Thus facilitating the incorporation of biological noise such as different cell cycle states or metabolic variations.