Guy Lamoureux,a,b* Mónica Alvarado-Rojas,a,b
a Escuela de Química, Universidad de Costa
Rica, 2060 San Pedro, San José, Costa Rica
b Centro de Investigación en Productos Naturales (CIPRONA), Universidad de Costa Rica, 2060 San Pedro, San José, Costa Rica
*Correspondence e-mail:
guy.lamoureux@ucr.ac.cr
The title
compounds, C20H20ClNO2 and C20H20BrNO2, are examples of naphthoquinones substituted with a bulky amine and halogen. These structures were determined at 100 K and both have monoclinic (P21/c) symmetry. Uniquely, these solid-state structures do not contain an intramolecular H-bond between the N-H and the carbonyl group. The enamine C—N bond length at C2 [1.353 (3) Å ], .
Keywords: crystal structure; adamantylamine; naphthoquinone.
Chemical Context
Naphthoquinones (naphthalenediones) form an important part of some pharmacophores in medicinal
chemistry.