Introduction

Pituicytomas (PCT), granular cell tumors (GCT) and spindle cell oncocytomas (SCO) are rare, intrinsic neoplasms of the sellar region.  As a group, they are classified as non-neuroendocrine World Health Organization Grade I tumors arising from the posterior pituitary \cite{Lopes2017}. Pituicytomas are characterized by their origin from pituicytes, a specialized glial cell found in the neurohypophysis2. Granular cell tumors of the neurohypophysis are masses of uncertain origin, but some studies suggest that these tumors originate from pituicytes3,4. Spindle cell oncocytomas of the adenohypophysis also have unclear cellular origins; however, Roncaroli et al5 suggests that SCOs are derived from folliculostellate cells, which are sustentacular cells of the adenohypophysis. A common histogenetic marker seems to be thyroid transcription factor 1 (TTF-1) expression, which has been recognized6 as positively staining in sellar region tumors, specifically towards pituicytes. 
Although all considered benign tumors, their progression can cause symptoms typical of sellar masses including headaches, endocrine abnormalities, and vision loss. When these lesions are symptomatic, treatment is indicated, however there is debate regarding management in the literature. To date there are limited surgical case series of these tumors, and most without long-term follow up. We present a single institutional series reporting clinical presentation, immunohistochemical results, and intraoperative and postoperative findings.