An example of PLS-DA for DNA adductome profile in the amphipod Monoporeia affinis from different sites in the Baltic Sea (A); modified from \cite{Martella2023}. The data points represent the samples collected in the stations classified as contaminated (C; red) or reference (R; green); the labels indicate the station codes. In this example, none of the samples collected from the contaminated stations aligned with the ordination space of the reference samples. The B-panel shows a separation based on the DNA adductome between field-collected females carrying different proportions of embryos with developmental aberrations and classified as Healthy (H: aberration frequency is less than 5 %) and Unhealthy (U: up to 60 %); modified from \cite{Gorokhova2020}.