4 DISCUSSION
The break of HAdV7 infection in a tertiary hospital that led to a death
case and nosocomial infection was describes. There were no a standard
fever clinic in the hospital and no strict infection control procedures
when caring for the patients, which were the main causes of the
outbreak. Some doctors and nurses have not adopted these infection
control precautions properly (even badly no wearing surgical masks) due
to weak control awareness, which contributed to the virus transmission.
Large community outbreaks of acute respiratory disease caused by HAdV7
with severe outcomes have been reported. Thus, control of HAdV7 spread
is crucial. However, difficulties of differentiating pneumonia caused by
HAdVs from other types of pneumonia and recognition of HAdV7 infections
promoted the transmission to a large extend.
In the investigation, it was concluded that 13 patients were infected by
the index case after first contact with him. A strict infection control
procedure with the use of disposable protection suit and gloves, strict
hand hygiene, and disinfection of public place (such as floors and
toilets), was initiated immediately when the pathogen was identified.
The 13 confirmed cases were medical treatment in single rooms and the 7
symptomatic patients had recovered well after 5 to 8 days of
hospitalization. The 6 silent-infection cases and other close contacts
were treated with temperature and symptom monitoring for 8 days, which
were all asymptomatic and removed from medical observation.
In summary, hospital infections are transmitted when the officials
become self-content and personnel do not abide by correct hygiene rules.
We suggest that more importance should be given to the early diagnosis
of HAdV7. Hospitals should set up a standard fever clinic (especially in
regular influ season), improve their diagnostic capabilities for rapid
detection of HAdV and reinforce the management of nosocomial infections.