4 DISCUSSION
The break of HAdV7 infection in a tertiary hospital that led to a death case and nosocomial infection was describes. There were no a standard fever clinic in the hospital and no strict infection control procedures when caring for the patients, which were the main causes of the outbreak. Some doctors and nurses have not adopted these infection control precautions properly (even badly no wearing surgical masks) due to weak control awareness, which contributed to the virus transmission.
Large community outbreaks of acute respiratory disease caused by HAdV7 with severe outcomes have been reported. Thus, control of HAdV7 spread is crucial. However, difficulties of differentiating pneumonia caused by HAdVs from other types of pneumonia and recognition of HAdV7 infections promoted the transmission to a large extend.
In the investigation, it was concluded that 13 patients were infected by the index case after first contact with him. A strict infection control procedure with the use of disposable protection suit and gloves, strict hand hygiene, and disinfection of public place (such as floors and toilets), was initiated immediately when the pathogen was identified. The 13 confirmed cases were medical treatment in single rooms and the 7 symptomatic patients had recovered well after 5 to 8 days of hospitalization. The 6 silent-infection cases and other close contacts were treated with temperature and symptom monitoring for 8 days, which were all asymptomatic and removed from medical observation.
In summary, hospital infections are transmitted when the officials become self-content and personnel do not abide by correct hygiene rules. We suggest that more importance should be given to the early diagnosis of HAdV7. Hospitals should set up a standard fever clinic (especially in regular influ season), improve their diagnostic capabilities for rapid detection of HAdV and reinforce the management of nosocomial infections.