4. Conclusion
Currently, the drug curcumin has been absorbed and examined using
metal-organic framework nanocomposites. Magnetic metal-organic framework
nanocomposites with ferrite nickel weight ratios of 30, 10 and 50 to
silica matrix were synthesized by the in-situ self-arrangement method.
These magnetic metal-organic nanocomposites were identified by XRD, TEM,
SEM, VSM and BET analysis and from their comparison with the
authorities, the accuracy of the synthesis was obtained. To study the
nanocomposites of the synthesized magnetic metal-organic framework as
the adsorbent and drug interaction of curcumin, absorption parameters
such as adsorbent type, adsorbent dose and drug dose were investigated.
Finally, the optimal conditions were introduced using these
metal-organic frameworks nanocomposites. Magnetic metal-organic
frameworks nanocomposite with ferrite nickel ratio of 30% by weight to
silica matrix acted as the best adsorbent with the highest capacity to
absorb curcumin. The results of drug uptake and interaction by this
nanocomposite showed a synthesized magnetic metal-organic framework in
an environment with pH=7, contact time 8 hours, the dose of drug 10 ppm
and the amount of adsorbent double of the dose of the drug are the
optimum values for achieving the maximum