4. Conclusion
Currently, the drug curcumin has been absorbed and examined using metal-organic framework nanocomposites. Magnetic metal-organic framework nanocomposites with ferrite nickel weight ratios of 30, 10 and 50 to silica matrix were synthesized by the in-situ self-arrangement method. These magnetic metal-organic nanocomposites were identified by XRD, TEM, SEM, VSM and BET analysis and from their comparison with the authorities, the accuracy of the synthesis was obtained. To study the nanocomposites of the synthesized magnetic metal-organic framework as the adsorbent and drug interaction of curcumin, absorption parameters such as adsorbent type, adsorbent dose and drug dose were investigated. Finally, the optimal conditions were introduced using these metal-organic frameworks nanocomposites. Magnetic metal-organic frameworks nanocomposite with ferrite nickel ratio of 30% by weight to silica matrix acted as the best adsorbent with the highest capacity to absorb curcumin. The results of drug uptake and interaction by this nanocomposite showed a synthesized magnetic metal-organic framework in an environment with pH=7, contact time 8 hours, the dose of drug 10 ppm and the amount of adsorbent double of the dose of the drug are the optimum values for achieving the maximum