3.1 Literature Search
As shown in Figure 1, these were the detailed steps for our literature
retrieval. According to the retrieval method, 11,676 potential related
citations were retrieved. After screening, this meta-analysis included
57 studies [9-65]. All studies conformed to the
requirements of EGFR-TKIs regimen combined with TCMs interventionversus EGFR-TKIs regimen solely. ORR was
provided in a similar manner. The 57 studies were classified as capsules
(7 studies),
granule
group (2 studies),
decoction
group (22 studies), TCM differentiation group (5 studies)
and injection
group (21 studies), there were a total of 4266 individuals, 2161 in the
experimental group and 2105 in the control group. Table 1 summarizes the
clinical characteristics of all participants, including TCM intervention
dose, sample size, duration, dose, and cycle of EGFR-TKIs regimen.