3.1 Literature Search
As shown in Figure 1, these were the detailed steps for our literature retrieval. According to the retrieval method, 11,676 potential related citations were retrieved. After screening, this meta-analysis included 57 studies [9-65]. All studies conformed to the requirements of EGFR-TKIs regimen combined with TCMs interventionversus EGFR-TKIs regimen solely. ORR was provided in a similar manner. The 57 studies were classified as capsules (7 studies), granule group (2 studies), decoction group (22 studies), TCM differentiation group (5 studies) and injection group (21 studies), there were a total of 4266 individuals, 2161 in the experimental group and 2105 in the control group. Table 1 summarizes the clinical characteristics of all participants, including TCM intervention dose, sample size, duration, dose, and cycle of EGFR-TKIs regimen.