Nuchal oedema n = 40 (38.5%) Subcutaneous oedema or hydrops n = 64 (61.5%) Total N = 104
Maternal age (years) 32.6 (30.1-37.5) 33.7 (30.6-37.8) 33.6 (30.3-37.6)
Weight (Kg) 61.0 (53.9-72.3) 64.0 (58.0-70.0) 64.0 (55.3-70.0)
Height (cm) 160.5 (158.0-166.5) 163.0 (158.0-169.0) 162.0 (158.0-168.0)
Body mass index (kg/m2) 23.0 (20.0-27.8) 23.9 (21.1-26.3) 23.4 (20.8-26.9)
Parity
Nulliparous
19 (47.5)
33 (51.6)
52 (50.0)
Parous
21 (52.5)
31 (48.4)
52 (50.0)
Previous chromosomal abnormality 2 (5.0) 4 (7.8) 7 (6.7)
Gestational age at pre-NIPT ultrasound (weeks) 10.5 (10.4-10.7) 10.6 (10.4-10.9) 10.6 (10.4-10.9)
Conception
Spontaneous
36 (90.0)
56 (87.5)
92 (88.5)
IVF
4 (10.0)
8 (12.5)
12 (11.5)
Crown-rump length (mm) 39.4 (35.8-40.7) 39.4 (36.0-41.6) 39.4 (26.0-41.3)
Oedema thickness ≤ 10+6 weeks (mm) 3.2 (2.6-3.8) 3.1 (2.5-4.1) 3.1 (2.5-4.1)
Nuchal translucency 11-13+6 weeks (mm) 2.5 (2.2-3.0) 2.4 (1.9-3.2) 2.5 (2.0-3.1)
High risk cell-free DNA test 2/34 (5.9) 5/51 (9.8) 7/85 (8.2)