Figure 7. Estimating intrinsic gating from a CRC.
Unliganded gating equilibrium constants (E0) estimated
from CRC parameters (Table 1). The assumed η values were either 52%
(red) or 40% (blue). The calculated E0 is approximately
the same regardless of η and close to the actual value of 4.5 x
10‑7 (dashed line).
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