We also analyzed the activity of both types of enzymes in corals used in the venetoclax experiment to reject the possibility that upon treatment, corals switched the effector PCD pathway involved in bleaching (Figure 5A). All samples were taken on day 5 of the experiment. We did not see any significant upregulation of caspase-3 in any treatment combination (ven-HT or ven+HT) but we observed significant differences in APs activity (ANOVA, activity ~ treatment + conditioning + (1|coral)). AP activity varied between venetoclax treatments (p = 0.01783) and between conditioning treatments (p = 0.01285). Overall, these results suggest that corals do not switch between PCD pathways during Bcl-inhibition treatment.