NFkB is a pleiotropic transcription factor involved in many crucial cellular processes, including stress response and innate immunity in invertebrates (Gilmore & Wolenski, 2012; Virginia M Weis, 2019). It is tightly bound to its inhibitor (NFKBI) in the cytoplasm and requires dissolution from the complex prior to its activation (reviewed in (Luo, Kamata, & Karin, 2005). Our results show the expression rate of pa-NFKBI is higher in PC corals both prior and throughout the stress test (Figure 5B, p(conditioning) <0.001, p(0h) = 0.054, p(72h) < 0.001).