FIGURE 3. HSG4112 ameliorates fatty liver in HFD-mice. (A) Representative image of liver and its histological section stained with H&E (n = 10). Standard bar = 200µm. (B) Quantification of liver weight. (C-F) NAS and fibrosis score on liver histology; in detail, (C) steatosis score, (D) lobular inflammation score, (E) NAS score, (F) fibrosis score. (G-K) Serum parameters associated with fatty liver; (G) triglyceride, (H) LDL-cholesterol, (I) HDL-cholesterol, (J) total cholesterol, (K) AST, (L) ALT. #P < 0.05, ###P < 0.001 vs. Normal group, ***P < 0.001 vs. Vehicle group, and n.s. = not significant; one-way ANOVA with Tukey’s multiple comparison test. No statistically significant difference observed for all comparisons of HSG4112 group vs. Normal group. All data represent terminal values of mean ± SEM.