Fig. 4 HSG4112 regulates metabolic gene expression in HFD-induced obese mice. Relative gene expression was measured using qRT-PCR (n = 4) on terminal a gastrocnemius muscle, b liver, c hypothalamus, and d interscapular adipose tissue (BAT) collected from HFD-induced obese mice orally administered with 100 mg·kg-1 dose for 6 weeks. One-way ANOVA with Tukey’s multiple comparison test was performed; *P < 0.05, **P < 0.01 vs. Vehicle group, #P < 0.05, ##P < 0.01 vs. Normal group.