Fig. 5 HSG4112 ameliorates fatty liver in HFD-induced obese mice orally administered with 100 mg·kg-1 dose for 6 weeks (n = 10) a Representative image of liver and its histological section stained with H&E. Standard bar = 200µm. b Quantification of liver weight. c-f NAS and fibrosis score on liver histology: c steatosis score, d lobular inflammation score, e NAS score, and f fibrosis score. g-l Serum parameters associated with fatty liver: g triglyceride, h LDL cholesterol, i HDL cholesterol, j total cholesterol, k AST, and l ALT. All data represent terminal values of mean ± SEM. One-way ANOVA with Tukey’s multiple comparison test was performed; n.s. = not significant, #P < 0.05, ###P < 0.001 vs. Normal group, ***P < 0.001 vs. Vehicle group.