Figure 6 YDZG ameliorates LPS-induced acute lung injury in
mice. (A) Twenty mice per group were pretreated with vehicle or YDZG
(10 mg·kg-1, i.v.) for 2 h before a lethal dose of LPS
(15 mg·kg-1, i.t.) injection. DEX (5
mg·kg-1, i.p.) was used as a positive control. The
survival rates of these mice were observed for the next 120 h. Mice were
treated with LPS and YDZG as described in the Material and Methods
section. (B) Resistance of lung (RL), resistance of expiration (Re) and
respiratory lung compliance (Cdyn) were detected using an AniRes2005
lung function test system (n=8). (C) Lung histopathology at 24 h after
LPS challenge (n=8). Data are reported as mean ± SEM; *P <
0.05 compared with the LPS alone group.