Supplementary figure5. Ziyu II enhances the anti-cancer efficacy of 5-Fluorouracil in colorectal cancer cells (A ). Cell growth of CRC cells treated with the indicated dose of Ziyu II in combination with 5-FU. (B ). Colony formation assay of CRC cells treated with or without 15 μM Ziyu II in the presence or absence of 10 μM 5-FU. Representative images (B ) and quantification of colonies (C) were shown. ***, p < 0.001.