Figure 1. Tfh cells and the age at menarche. (A), Flow analysis
of Tfh1, Tfh2 and Tfh17 cells. (B), Association between the subgroups of
Tfh cells with the age at menarche.
Figure 2. Correlation between pre-pregnancy Tfh1/Tfh2
and TSH at early pregnancy.
Figure 3. The rate of spontaneous miscarriage, plotted against
time through 15 months of follow-up. (A), categorized by AAM. (B),
categorized by ratio of Tfh1/Tfh2
Figure S1. Comparison of pre-pregnancy Tfh1/Tfh2 ratio in
healthy pregnancies (H), threatened miscarriages (T) and spontaneous
miscarriages (S) .
Figure S2. The causal relationship between AAM and Tfh cells:
MR test between AAM and PD1- naïve Tfh cells, and the
shared genetic loci between them: rs1933801 (LIN28B ) and
rs1516883 (Chromosome 9p12: LINC01505, TAL and TMEM38B ).