Figure 1. Tfh cells and the age at menarche. (A), Flow analysis of Tfh1, Tfh2 and Tfh17 cells. (B), Association between the subgroups of Tfh cells with the age at menarche.
Figure 2. Correlation between pre-pregnancy Tfh1/Tfh2 and TSH at early pregnancy.
Figure 3. The rate of spontaneous miscarriage, plotted against time through 15 months of follow-up. (A), categorized by AAM. (B), categorized by ratio of Tfh1/Tfh2
Figure S1. Comparison of pre-pregnancy Tfh1/Tfh2 ratio in healthy pregnancies (H), threatened miscarriages (T) and spontaneous miscarriages (S) .
Figure S2. The causal relationship between AAM and Tfh cells: MR test between AAM and PD1- naïve Tfh cells, and the shared genetic loci between them: rs1933801 (LIN28B ) and rs1516883 (Chromosome 9p12: LINC01505, TAL and TMEM38B ).