Study Design and Settings
The prospective cohort study included pregnant women with SCD at the Korle-Bu Teaching Hospital (KBTH), Ghana, from May 2015 to December 2016. The primary outcomes of the study were maternal and perinatal mortality rates. KBTH is a tertiary referral hospital in Ghana’s capital, Accra, and the largest specialist hospital in Ghana. The maternity unit attends to about 11 000 pregnant women annually including ~200 pregnant women with SCD.