Precautions in Perinatal Period
The physiological changes of pulmonary function during pregnancy
increase the susceptibility and severity of
pneumonia10. Early studies have shown that prenatal
pneumonia is associated with high perinatal mortality and therefore
requires active treatment to prevent and correct maternal hypoxia, which
include: oxygen inhalation to keep oxygen saturation above 95%;
hydration support; timely considering delivery to improve maternal
oxygenation; empirical antibiotics to prevent secondary bacterial
infections. Administration of Betamethasone 12mg intramuscularly
followed by another dose 24 hours later to promote fetal lung maturity
when preterm delivery is anticipated.
At present, there is no study on the vaginal mucosa or secretion samples
of pregnant women infected with COVID-19, but based on the previous
study results on tubular virus (HCoV), we should try to avoid the
exposure of newborns with all maternal body fluids. The specific
measures include: Individualize the mode of delivery according to the
specific conditions of the gestational age and delivery conditions;
sucking the nasopharynx before the first breath of the baby; no delayed
cord ligation and clean the mother’s blood and amniotic fluid as soon as
possible; infected or suspected mothers should avoid breastfeeding until
recover completely or has been confirmed not to have COVID-19.
Management of Gynecological Cancer Patient s
The novel coronavirus is more susceptible to infection in gynecological
cancer patients due to the systemic immunosuppressive state caused by
the malignancy itself, or surgery/radiotherapy and chemotherapy.
Standardized management should be implemented for gynecological cancer
patients to achieve scientific and accurate protection.
Patients who need surgery should be individualized according to their
condition. In case of life-threatening conditions, such as rupture or
bleeding of gynecological tumor, emergency operation and treatment
should be carried out on the premise of adequate protection. The
epidemic investigation should be further improved when the condition is
stable. Patients with advanced tumor or rapid progress of disease should
be treated as early as possible and those with precancerous lesions,
such as cervical intraepithelial lesions, should be treated as soon as
possible after the epidemic situation is stable.
For patients with severe myelosuppression, fever or the elderly and
other high-risk groups receiving chemotherapy for malignant tumors,
G-CSF and GM-CSF can be used prophylactically after chemotherapy to
avoid leucopenia and improve immunity. Fever after operation or
chemotherapy should be differentiated fromovel coronavirus infection. CT
examination should be performed again if necessary and with isolation of
the infected patients as soon as possible.