Treatment
Early identification and isolation are imperative for COVID‐19 control.
Those diagnosed with infection should be promptly admitted to a negative
pressure isolation ward. For patients with severe acute respiratory
distress syndrome, inhaled nitric oxide, high frequency oscillatory
ventilation and extracorporeal membrane lung may be useful. In addition,
the convalescent serum of SARS-CoV-2 recovered patients may be used for
SARS-CoV-2 infection, because the mortality of SARS convalescent
patients after treatment is significantly reduced8.
In China, antiviral therapy has been routinely used for the treatment of
COVID-19 and is also recommended for pregnant patients. The combination
of lopinavir/ ritonavir and Antiproteinase therapy is the first choice.
and α-interferon is inhaled by atomization. In addition, Remdesivir and
chloroquine are promising anti-COVID-19 drugs as they can inhibit
SARS-CoV-2 virus in vitro9. Antibiotics should be used
if there is evidence of secondary bacterial infection and
corticosteroids are generally not recommended for the treatment of
COVID-19, as it may delay the removal of virus.
Because COVID-19 might increase the risk for pregnancy complications,
management should be in a medical institution with close maternal and
infant monitoring. Data on COVID-19 and SARS in pregnancy are sparse. In
the two reports describing 18 cases of pregnancy with COVID-19, all of
them were infected in the third trimester, and clinical manifestations
were similar to those of non-pregnant adults. In the case of SARS, the
mortality rate of the largest 12 pregnancies was 25%. Complications
included ARDS in four, DIC in three, renal failure in three, bacterial
pneumonia in two and sepsis in two cases.