Imbalance
of Th17 and Tregs inthymoma may be a
pathological mechanism ofmyasthenia gravis
Short title: Imbalance of Th17 and Tregs in thymoma with MG
Yuan Chen, Xuesong Zhang, Yuanguo Wang, Chao Lu, Jian Li, Peng Zhang*
Department of Cardiothorcic surgery, Tianjin Medical University General
Hospital, Tianjin/China, Zip Code: 300052
Address correspondence and reprint requests to Dr. Peng Zhang,
Department of Cardiothorcic surgery, Tianjin Medical University General
Hospital, Tianjin/China, Zip Code: 300052, E-mail: zhangpengtjgh@126.com
Key Words:thymoma, myasthenia gravis, Th17, Treg, IL-6
Abbreviations used in this article: MG, myasthenia gravis; Th17, T
helper type 17, Treg, T regulatory cells; RORγt, Retinoid-related orphan
receptors gamma t; FOXP3, Forkhead transcription factor 3; PBMC,
Peripheral blood monocyte; FCM, flow cytometer cytometry; ELISA,
enzyme-linked immunosorbent assay.