Strengths and Limitations
As a COVID-19-designated hospital in Wuhan, the pregnant women with suspected and confirmed COVID-19 were admitted to our hospital. During the epidemic, cesarean section and general anesthesia were preferred to ensure that the delivery process is controllable, and to reduce emergency respiratory problems and reduce the risk of exposure to others. But the effects of these measures have not been fully proven6,7,8. During the epidemic, choosing cesarean section blindly will cause the long-term adverse effects on women undoubtedly. This study analyzed the pneumonia conditions, delivery conditions, delivery outcomes, and neonatal infections in pregnant women with COVID-19, and evaluate the effect  of vaginal delivery on pregnant women with COVID-19 and their newborns. Based on the above data, we provided more suggestions for the choice of delivery mode for pregnant women during the COVID-19 epidemic, summarized the methods of infection prevention during vaginal delivery and provide effective measures to avoid medical staff infection.
However, this study is limited by the small sample size, as the number of pregnant women with clinically confirmed COVID-19 underwent vaginal delivery is relatively small. This group of pregnant women are in accordance with the clinical diagnostic criteria for COVID-19 in China, but the pathogenic diagnosis is negative, but the false-negative results of SARS-CoV-2 nucleic acid throat swabs could not be excluded completely. For clinically diagnosed cases, close follow-up observation would be required. In addition, for pregnant women with COVID-19 underwent vaginal delivery, it can provide an indirect etiology basis for the existence of neonatal infection if the SARS-CoV-2 nucleic acid detection of amniotic fluid, vaginal secretions and perianal secretions can be performed.