The psychomotor effects of amphetamine in SERT+/+ and SERT−/− rats.
AMPH resulted in a dose-dependent increase in locomotor activity over time (Fig 2: amphetamine dose x time effect: F(8,372)=36.688, p<0.05). This increase in locomotor activity was stronger in SERT-/- compared to SERT+/+ rats (Fig 2: genotype x amphetamine dose x time effect: F(8,372)=2.468, p <0.05).